There is a hitherto secret messenger between fatty tissue and the brain that helps maintain good energy in the body. The researchers of the Scripps research (California), highlighting the role of adipose tissue sensory neurons in fat burning.
In the midst of the complex interplay between our genes, our environment, our diet and oursthere is another communication network between the and adipose tissue that exchange information.
Researchers have long known that fat givesit is composed of neurons, but they assumed it in adipose tissue were connected to the sympathetic nervous system – the one that governs the automatic and unconscious reactions of our body, such as fat in case of stress and activity .
Indeed, we have a sensory nervous system that carries messages “on the other side,” from adipose tissue to the brain. ” The discovery of these neurons suggests for the first time that the brain actively monitors adipose tissue and does not just passively receive messages about it. “, To explainthe co-author of Li Ye, associate professor of neuroscience at Scripps research.
Two new methods for understanding the role of sensory neurons
However, by studying thedeep in the fatty tissue it was more complex than in the brain, because the nerves there are difficult to see or stimulate. The researchers then used two new methods. It allows to obtain fabrics using to delete the which give the fabrics their opacity. In mice, the researchers found that nearly half of the fat neurons did not connect to the sympathetic nervous system, but to the sensory nervous system.
The second new technique allowed them to understand the role of thesein the adipose tissue. Named ” »Makes it possible to target and thus destroy subsets of neurons. When used, the suppression of sensory messages from adipose tissue resulted in an increase in fat in mice, particularly brown fat. Since this fat helps our body to convert the and other fats the mice also had a higher.
Regulation in fat burning
” This tells us that there is more than just an instruction that the brain sends to the fatty tissue.says Li Ye. It’s more nuanced than that: these two types of neurons act as an accelerator and brake for fat burning. “.
In fact, the sensory neurons that innervate adipose tissue regulate fat by acting as a brake on adipose tissuenice. Conversely, sympathetic neurons are needed to activate fat burning and brown fat production.
Whether researchers believe this mode of communication is essential for maintaining “healthy fat” remains to be seen what is the content of the messages that sensory neurons transmit to the brain from adipose tissue. The team plans future research to find out what neurons detect and whether similar cells exist in other internal organs.