Stroke before age 60: do you have a blood group at risk?

Stroke before age 60: do you have a blood group at risk?

Stroke before age 60: do you have a blood group at risk?

There are two types of stroke. Hemorrhagic stroke occurs when an artery in the brain ruptures and blood flow causes brain cell death. Ischemic stroke is characterized by an obstruction of an artery. It can be blocked by a blood clot or fat deposit. The blocked area is no longer irrigated with blood. Without oxygen supply, the area can therefore be irreversibly affected. To find out who might be more prone to ischemic stroke before age 60, the University of Maryland conducted an extensive meta-analysis published in the journal Neurology. Their findings suggest that there is indeed a difference in risk based on blood group.

Most strokes occur later in life. For this reason, we chose a 60-year limit for our study to partially include stroke cases that are relatively young compared to the age at which strokes usually develop.“Explains Dr. Braxton Mitchell, a specialist in epidemiology and public health at Science and the future. For this, the team looked at 48 written studies on the subject, including 17,000 stroke victims and 600,000 control patients, who have never had an ischemic stroke. All were between 18 and 59 years old.

At more risk than O

The results showed that there is indeed a difference between blood groups. People with type A had a 16% higher risk of early stroke than those with different blood groups. People with blood type B had an 11% higher risk of having a stroke. People with type O were 12 percent less likely to have an early stroke than those with other blood types. In addition, the link between blood type and the onset of a stroke was very strong for early strokes.

But this link was weaker for strokes that occur later in life. The researchers used another data sample of 9,300 people with strokes and 25,000 without strokes, this time over the age of 60. It was found that with age the link between group A and increased risk no longer appeared significant. Group B still had an 11% higher risk, as for patients under the age of 60.

Why should group A be more at risk than group O before the age of 60? The team has not, at this time, determined a cause. “However, we believe that the blood group predisposes people to clotting“explains Dr. Mitchell to Science and the future. Excessive blood clotting leads to the appearance of blood clots, which are responsible for the onset of ischemic stroke. “We also find that blood group A is associated with early venous thromboembolism, another clotting disorder.Another clue that could guide researchers into future work.

No problem if you are part of group A

The study authors are formal: People whose blood type is A shouldn’t worry too much. There is no need to undergo screening tests or special doctor visits. “Importantly, people with group A blood should not be particularly concerned about the risk of stroke. Blood group is a much weaker risk factor than other modifiable stroke risk factors, such as high blood pressure and smoking. For people who want to reduce their risk of stroke, these are the main factors to consider. “

Regardless of blood type, taking care of your hypertension and quitting smoking are the two most important ways to deal with stroke risk. Furthermore, specialists do not rule out that blood group A accentuates the effects of hypertension and smoking on stroke; highlight the need for further studies to better understand the phenomenon. Note that during a Covid-19 study, group O also appeared to be more protective, while group A presented more risks.

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